Preparation of Aromatic Nitriles from Aromatic Primary Amines using Tetracyanonickelate (II)

Preparation of sterically congested 1,3,4-oxadiazole derivatives from N-isocyaniminotriphenylphosphorane, aromatic acids, cyclopentanone and primary amines

Reactions of N-isocyaniminotriphenylphosphorane with cyclopentanone have been studied in the presence of aromatic carboxylic acids and primary amines, proceeds smoothly at room temperature under neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives by an intramolecular Aza-Wittig cyclization in CH2Cl2 in excellent yields. The structures of the products were deduced from...

Trimereation of Aromatic Nitriles

preparation of sterically congested 1,3,4-oxadiazole derivatives from n-isocyaniminotriphenylphosphorane, aromatic acids, cyclopentanone and primary amines

reactions of n-isocyaniminotriphenylphosphorane with cyclopentanone have been studied in the presence of aromatic carboxylic acids and primary amines, proceeds smoothly at room temperature under neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives by an intramolecular aza-wittig cyclization in ch2cl2 in excellent yields. the structures of the products were deduced from...

Aromatic Iodides from Aromatic Organomercurials 13.2. Aromatic Bromides from Aromatic Organomercurials 13.3. Aromatic Chlorides from Aromatic Organomercurials 13.4. Aromatic Fluorides from Aromatic Organomercurials 13.5. Aromatic Nitriles from Aromatic Organomercurials 14. Improved Syntheses of Some Diaryliodonium Salts from Symmetric Diarylmercurials

This review reports some novel (or improved) synthetic methods for preparing a number of aromatic (carbocyclic and predominantly heterocyclic) organomercurials, particularly those derived from theophylline, theobromine and uracil, as well as some novel haloand cyano-demercuration reactions. We have also synthesized the first stable organic derivative of mercury(I), viz. 1,8-bis(acetoxydimercuri...

Nitrosamines and Aromatic Amines

A new method for the simultaneous determination of hemoglobin adducts from aromatic amines and tobacco-specific nitrosamines (TSNA) is described. After mild base-catalysed hydrolysis releasing aromatic amines and the TSNA adduct 4-hydroxy-1-(3-pyridyl)-1butanone (HPB), the extraction, cleanup, and concentration are performed by a one-step procedure using C 1 8 cartridges. Determination in the p...